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Table 2 Clinical course, age and gender distribution of the studied CLN3 patients who did not receive anticonvulsants.

From: Analysis of Potential Biomarkers and Modifier Genes Affecting the Clinical Course of CLN3 Disease

Clinical course

Patient

Age (years)

Gender

Index of Relative Severity

Rapid

1

12

F

−1.4

 

2a

12

F

−0.8

Slow

3

29

M

1.2

 

4

28

M

0.8

Average

5a

18

F

−0.1

 

6b

10

M

0

 

7b

9

F

−0.3

 

8

12

M

−0.3

  1. aSiblings family 1.
  2. bSiblings family 2.