Table 4 List of genes that were significantly dysregulated in all CLN3 patients.
From: Analysis of Potential Biomarkers and Modifier Genes Affecting the Clinical Course of CLN3 Disease
Fold change | ||||
|---|---|---|---|---|
Gene symbol | Gene name | Rapid | Average | Slow |
POLR2J2 | DNA-directed RNA polymerase II polypeptide J-related | −2.2 | −1.7 | −2.6 |
CDC42SE2 | CDC42 small effector 2 | −3.2 | −1.8 | −2.5 |
RGS1 | Regulator of G protein signaling 1 | +1.9 | +2.5 | +1.8 |
DUSP2 | Dual specificity phosphatase 2 | +2.3 | +2.4 | +2.4 |
PARP15 | Poly(ADP-ribose) polymerase family member 15 | +1.5 | +1.7 | +1.8 |