Figure 2
From: Targeting Inflammation in Heart Failure with Histone Deacetylase Inhibitors
In vivo activities of HDAC inhibitors in rodent heart failure models. The indicated compounds have been tested in rodent models of heart failure. Models in which the compounds have demonstrated efficacy are shown, as are the relative potencies of compounds for different HDAC classes. The structure of apicidin-derivative (Api-D) is not available (N/A). Angll, angiotensin II; ISO, isoproterenol; PAB, pulmonary artery banding; RV, right ventricle.