Figure 4

Effect of pHBSP on pulmonary congestion. Lung histological sections taken from a sham-operated rat with congestion grade 0 (A); a rat subjected to HS with congestion grade 3 (B); and a rat subjected to HS and administered 1 µg/kg pHBSP 60 min after the onset of resuscitation with congestion grade 0 (C). Hematoxylin and eosin, magnification 400×, figures are representative of at least three experiments performed on different days. Effect of pHBSP on pulmonary congestion (D) after sham operation (Sham, n= 3) or HS (HS + saline, n= 3; HS + pHBSP 60 min after resuscitation [1 µg/kg 60 min after the onset of resuscitation], n = 3). Data represent mean ± SEM for n observations, ⋆P < 0.05 HS + saline.