Table 1 Correlation between the expression of H3K27me3 and clinicopathologic features in nasopharyngeal carcinomas.
H3K27me3 protein | ||||
|---|---|---|---|---|
All cases | Low expression | High expression | P valuea | |
Sex | 0.560 | |||
Female | 59 | 25 (42.4%) | 34 (57.6%) | |
Male | 150 | 57 (38.0%) | 93 (62.0%) | |
Age at diagnosis (years) | 0.583 | |||
≤45 | 89 | 33 (37.1%) | 56 (62.9%) | |
>45 | 120 | 49 (40.8%) | 71 (59.2%) | |
Histological classification (WHO)b | 0.363 | |||
Type II | 54 | 24 (44.4%) | 30 (55.6%) | |
Type III | 155 | 58 (37.4%) | 97 (62.6%) | |
T classification | 0.000 | |||
1 | 26 | 19 (73.1%) | 7 (26.9%) | |
2 | 68 | 37 (54.4%) | 31 (45.6%) | |
3 | 69 | 17 (24.6%) | 52 (75.4%) | |
N classification | 0.024 | |||
0 | 40 | 23 (57.5%) | 17 (42.5%) | |
1 | 96 | 34 (35.4%) | 62 (64.6%) | |
2 | 51 | 15 (29.4%) | 36 (70.6%) | |
Distant metastasis | 0.021 | |||
0 | 158 | 69 (43.7%) | 89 (56.3%) | |
1 | 51 | 13 (25.5%) | 38 (74.5%) | |
Clinical stage | 0.000 | |||
I | 10 | 8 (80.0%) | 2 (20.0%) | |
II | 55 | 37 (67.3%) | 18 (32.7%) | |
III | 83 | 23 (27.7%) | 60 (72.3%) | |
RT response | 0.505 | |||
CR | 31 | 23 (74.2%) | 8 (25.8%) | |
IC/RT response | 0.016 | |||
CR | 67 | 29 (43.3%) | 38 (56.7%) | |
Non-CRc | 21 | 3 (14.3%) | 18 (85.7%) | |
IC/CRT response | 0.006 | |||
CR | 66 | 32 (48.5%) | 34 (51.5%) | |
Non-CRc | 13 | 1 (7.7%) | 12 (92.3%) | |