Table 3 Univariate and multivariate analysis of different prognostic variables in 209 patients with nasopharyngeal carcinoma.
Univariate analysisa | Multivariate analysisb | ||||
|---|---|---|---|---|---|
Variable | All cases | Mean survival (months) | Pvalue | Hazards ratio (95% CI) | P value |
Sex | 0.545 | ||||
Female | 59 | 128.9 | |||
Male | 150 | 158.5 | |||
Age at surgery (years) | 0.237 | ||||
≤45 | 89 | 119.4 | |||
>45 | 120 | 162.9 | |||
Histological classification (WHO) | 0.059 | ||||
Type II | 54 | 180.5 | |||
Type III | 155 | 120.3 | |||
T classification | 0.012 | 0.829 (0.444–1.549) | 0.557 | ||
T1–T2 | 94 | 158.5 | |||
T3–T4 | 115 | 142.5 | |||
N classification | 0.000 | 1.368 (0.815–2.297) | 0.235 | ||
N0–N1 | 136 | 172.2 | |||
N2–N3 | 73 | 79.1 | |||
Distant metastasis | 0.000 | 2.000 (1.217–3.289) | 0.006 | ||
0 | 158 | 171.2 | |||
1 | 51 | 69.3 | |||
Clinical stage | 0.000 | 1.836 (0.739–4.563) | 0.191 | ||
I–II | 65 | 175.7 | |||
III–IV | 144 | 140.0 | |||
Treatment regimen | 0.001 | 0.692 (0.493–0.972) | 0.034 | ||
RTd | 42 | 112.9 | |||
ICe/RT | 88 | 132.3 | |||
IC/CRTf | 79 | 185.3 | |||
H3K27me3 expression | 0.000 | 1.830 (1.040–3.220) | 0.036 | ||
Low | 82 | 172.7 | |||
High | 127 | 135.3 | |||