Figure 4

Changes in renal glomerular immunostaining of nephrin in WT and TRPV1^−/− mice after 4 wks of deoxycorticosterone acetate (DOCA)-salt treatment. (A) Representative immunostained kidney sections showing the immunostaining of nephrin in brown in control WT and TRPV1^−/− mice (a and b), and WT and TRPV1^−/− mice (c and d) treated with DOCA-salt. Magnification, 400×. (B) Bar graph shows the changes in renal glomerular immunostaining of nephrin in WT and TRPV1^−/− mice with or without DOCA-salt treatment. Values are mean ± SE (n = 7 to 8). *P < 0.05 compared to control WT or TRPV1^−/− mice; ^†P < 0.05 compared to DOCA-WT mice.