Table 1 Changes in metabolic and renal parameters in WT and TRPV1^−/− mice after 4 weeks of DOCA-salt treatment.

BW^c (g)

28.8 ± 0.4^d

28.2 ± 0.3

29.1 ± 0.5

29.7 ± 0.3

Kidney weight (mg/10 g of BW)

77.1 ± 1.5

76.5 ± 1.2

109.6 ± 3.6^e

113.6 ± 3.1^e

Urinary albumin (mg/24 h)

6.9 ± 0.8

6.2 ± 0.7

28.3 ± 4.8^e

83.7 ± 7.1^e,f

GSI^g

0.13 ± 0.03

0.09 ± 0.02

0.34 ± 0.04^e

0.74 ± 0.08^e,f

TIS^h

0.29 ± 0.10

0.21 ± 0.11

2.00 ± 0.31^e

3.14 ± 0.26^e,f