Table 1 Different HDAC inhibitors that have been studied in vitro and ex vivo for HIV-1 purging.
From: Histone Deacetylase Inhibitors for Purging HIV-1 from the Latent Reservoir
HDAC inhibitor | Assay | Reference |
|---|---|---|
Sodium butyrate | TE671/RD cells | |
TSA, TPX | U1, ACH2, J49, OM10.1 | |
VPA | U1, ACH2, HUT-78/IIIB/LAI | |
TSA | HeLa | |
VPA | RCT | |
SAHA | RCT | |
SAHA | J89, RCT | |
SAHA, IHI | U1, ACH2 | |
SAHA, VPA | U1, J-Lat | |
Oxamflatin, VPA, SAHA, TSA | ACH2, 8E5, J-Lat | |
SAHA, VPA | 24STNLESG, Hela | |
CG05, CG06 | ACH2 | |
ITF2357, VPA, IHI | ACH2, U1 | |
TSA, oxamflatin | A7 |