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Figure 4 | Molecular Medicine

Figure 4

From: Overexpression of M3 Muscarinic Receptor Is a Novel Strategy for Preventing Sudden Cardiac Death in Transgenic Mice

Figure 4

Comparison of the inward rectifier K+ current (IK1) and transient outward K+ currents (Ito) from both WT and M3Tg mice with or without myocardial I/R. (A) Raw traces of IK1 recorded from WT and M3Tg mice. (B) The averaged current density-voltage (I-V) relationships of IK1. (C) Raw traces of Ito recorded from WT and M3Tg mice. (D) In the average I-V relationships of Ito, there were no differences among the four groups. I-V curves, mean from at least eight cells for each condition. (E) Raw traces of ICa,L recorded from WT and M3Tg mice. (F) In the average I-V relationships of ICa,L, there were no significant differences between the four groups. I-V curves, mean from at least eight cells for each condition. The average data were presented as mean ± SEM.

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