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Figure 3 | Molecular Medicine

Figure 3

From: Mutation Pattern of Paired Immunoglobulin Heavy and Light Variable Domains in Chronic Lymphocytic Leukemia B Cells

Figure 3

Comparison of the pattern of R mutations in CDRs (upper row) and FRs (lower row) of paired IGHVs and IGKVs between κ-expressing normal B-cell Igs (left column) and κ isotype CLL Igs (right column). Left: The scatter plots related to normal κ isotype B-cell repertoire are derived with permission from Brezinschek et al. (14). Right: scatter plots obtained from our data on κ isotype CLL samples (see Figure 1B). rsp (ρsp), Spearman rank.

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Molecular Medicine

ISSN: 1528-3658