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Figure 4 | Molecular Medicine

Figure 4

From: Mutation Pattern of Paired Immunoglobulin Heavy and Light Variable Domains in Chronic Lymphocytic Leukemia B Cells

Figure 4

Splitting CLL samples into groups A and B on the basis of different mutation percentages between IGHVs and IGK/LVs. Scatter plot of the percentage of mutations in IGHV and IGK/LV pairings for samples displaying a <3% difference between IGHV and IGK/LV mutation percentages (group A) or ≥3% difference (group B), respectively (see Materials and Methods for details). (A) All CLL samples. (B) κ Isotype samples. (C) λ Isotype samples. Each dot represents one or more CLL samples; color ranges from light gray (one sample) to dark gray (four or more samples).

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Molecular Medicine

ISSN: 1528-3658