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Table 2 Lipid class comparison between lipid rafts and nonraft membranes in control subjects (NSL).

From: Severe Alterations in Lipid Composition of Frontal Cortex Lipid Rafts from Parkinson’s Disease and Incidental Parkinson’s Disease

  Nonrafts Lipid rafts
Sphingomyelin 1.97 ± 0.86 11.43 ± 1.44a
PC 9.86 ± 0.87 5.35 ± 0.49a
PS 10.85 ± 1.08 6.82 ± 0.50a
PI 3.67 ± 0.59 2.16 ± 0.17a
Phosphatidylglycerol 2.71 ± 0.58 0.70 ± 0.10a
PE 28.72 ± 1.82 20.97 ± 0.57a
Sulfatides 0.00 ± 0.00 10.56 ± 0.68a
Cerebrosides 0.00 ± 0.00 5.10 ± 0.79a
Cholesterol 27.68 ± 1.98 33.04 ± 1.18a
Free fatty acids 10.68 ± 0.92 2.17 ± 0.28a
Sterol esters 0.00 ± 0.00 1.68 ± 0.60a
Total neutral lipids 42.23 ± 2.66 36.90 ± 1.41
Total polar lipids 57.77 ± 2.66 63.09 ± 1.41
Phospholipid/cholesterol 2.15 ± 0.18 1.11 ± 0.06a
  1. Results are expressed as mole % and represent mean ± SEM.
  2. aP < 0.05 compared with nonrafts.