Figure 2
From: Tissue Factor-Dependent Chemokine Production Aggravates Experimental Colitis
TFlow mice present reduced inflammation and coagulation during experimental colitis. (A) Hematoxylin and eosin staining of colon sections of wild-type and TFlow mice show that inflammation is less prominent in TFlow than in wild-type mice. (B) The total histopathological score is reduced in TFlow mice in comparison to wild-type mice. (C) Granulocyte infiltration is specifically decreased in colon sections of TFlow mice compared with wild-type mice, as shown by LY-6G staining. (D) Decreased levels of inflammatory cytokines in colon homogenates of TFlow mice. (E) Reduced levels of fibrin(ogen) in TFlow mice compared with control animals. Data are means ± SEM (n = 7). *P < 0.05, **P < 0.01, *** P < 0.001.