Figure 5
From: Small-Interfering RNA-Eluting Surfaces as a Novel Concept for Intravascular Local Gene Silencing
SiRNA delivery optimization by different coatings shows the transfection efficiency with different amounts of siRNAs and different N/P ratios. The first y axis reflects the E-selectin receptor expression in %, whereby untreated cells stimulated with TNF-α were set to 100%. The second y axis shows the viability of ECs in % seeded on coating composed of different siRNA amounts and N/P ratios. The viability of untreated cells was set to 100%. Each bar represents the mean ± SD of n = 3. p* indicates statistical significance at a level of P < 0.05 compared with untreated cells.