Figure 1
From: Cannabinoid Receptor Type I Modulates Alcohol-Induced Liver Fibrosis
CB1 and CB2 expression in human ALD. CB1 immunohistochemistry performed in paraffin-embedded human liver tissues from patients with ALD. Strong CB1 positivity can be observed within fibrotic septa (brown color), whereas parenchyma remained negative (A: magnification 10×; B: magnification 40×). Shown are representative images. (C) CB1, (D) PCα1(I) and (E) CB2 mRNA from liver biopsies of ALD patients with different fibrosis stage, measured by TaqMan PCR and normalized to GAPDH (mean ± SD; *P < 0.05).