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Table 1 Sample characteristics.

From: CALHM1 P86L Polymorphism Modulates CSF Aβ Levels in Cognitively Healthy Individuals at Risk for Alzheimer’s Disease

  Cognitively healthy AD
  Female Male Female Male
Number of patients 34 12 141 62
CALHM1 rs2986017 C/C 16 5 73 35
CALHM1 rs2986017 C/T 15 6 62 22
CALHM1 rs2986017 T/T 3 1 6 5
APOE ε2/3 4 2 NDa ND
APOE °2/4 1 0 ND ND
APOE °3/3 16 6 ND ND
APOE °3/4 11 4 ND ND
APOE °4/4 2 0 ND ND
Age at sample (average) 62.9 64.3 73.4 70.4
MMSE (± SDb) 29.8 (± 0.5) 29.8 (± 0.4) 21.1 (± 5.6) 22.7 (± 5.0)
Aβ 1–40 pg/mL (average ± SD) 8732 ± 3568 8696 ± 3816 ND ND
Aβ 1–42 pg/mL (average ± SD) 381 ± 196 336 ± 177 475 ± 221 518 ± 278
  1. aND: not determined.
  2. bSD: standard deviation.