Table 3 Top inflammation- and immunity-related signaling pathways represented in the 1,638 gene probes differentially regulated between patients with septic shock in the four developmental-age groups.
Signaling pathway | P | Number of genes |
|---|---|---|
B-cell receptor signaling | 2.1×10−8 | 27 |
TREM1 signaling | 1.5×10−7 | 15 |
Pattern recognition receptor signaling | 3.6×10−7 | 17 |
NF-κB signaling | 1.8×10−6 | 25 |
Dendritic cell maturation | 1.6×10−5 | 22 |
Communication between innate and adaptive immunity | 1.7×10−4 | 13 |