|  |  | IgAD | GD | SLE | T1D | CD | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
 |  |  | OR |  | OR |  | OR |  | OR |  | OR |  |
Locus | Gene | SNP | (95% CI) | Pvalue | (95% CI) | P value | (95% CI) | P value | (95% CI) | P value | (95% CI) | P value |
1p13 | PTPN22 | rs2476601 |  |  |  |  | 1.35 (1.24–1.47) |
| 2.04 (1.81–2.29) |
| Â | Â |
1q25.3 | NMNAT2 | rs2022013 |  |  |  |  | 0.85 (0.79–0.90) |
| Â | Â | Â | Â |
1q31.2 | RGS1 | rs2816316 |  |  |  |  |  |  | 0.89 (0.84–0.95) |
| 0.80 (0.76–0.84) |
|
2q12.1 | ILWRAP | rs917997 |  |  |  |  |  |  |  |  | 1.19 (1.14–1.25) |
|
2q24 | IFIH1 | rs1990760 | 0.67 (0.59–0.76) |
|  |  | 1.17 (—) |
| 0.85 (0.81–0.90) |
| Â | Â |
2q32.2 | STAT4 | rs7574865 |  |  |  |  | 1.57 (1.49–1.69) |
| Â | Â | Â | Â |
2q33.2 | CTLA4 | 3 SNPs |  |  | 1.49 (1.34–1.66) |
|  |  | 0.85 (0.78–0.92) |
| 1.14 (1.09–1.19) |
|
3p14.3 | PXK | rs6445975 |  |  |  |  | 1.25 (1.16–1.35) |
| Â | Â | Â | Â |
3p21 | CCR1/CCR3 | 2 SNPs |  |  |  |  |  |  |  |  | 1.30 (1.23–1.39) |
|
3q25.33 | IL21A | rsl 7810546 |  |  |  |  |  |  | 1.09 (1.04–1.14) |
| 1.36 (1.29–1.44) |
|
3q28 | LPP | rsl 464510 |  |  |  |  |  |  |  |  | 1.29 (1.25–1.34) |
|
4q27 | IL2–IL21 | 2 SNPs |  |  | 0.87 (0.79–0.95) |
|  |  | 1.27 (1.15–1.39) |
| 0.74 (0.70–0.78) |
|
5p13 | IL7R | rs6897932 |  |  |  |  |  |  | 0.89 (0.84–0.94) |
| Â | Â |
6p21.32 | HLA | Multi-SNPs | 2.53(2.17–2.95) |
| 4.6 (—) |
| 2.36 (2.11–2.64) |
| 6.85 (—) |
| 6.23 (5.95–6.52) |
|
6q21 | ATG5 | rs573775 |  |  |  |  | 1.19 (1.12–1.27) |
| Â | Â | Â | Â |
6q23.3 | TNFAIP3 | 3 SNPs |  |  |  |  | 1.17(1.10–1.25) |
| 0.90 (0.86–0.95) |
| 1.23 (1.17–1.28) |
|
6q25.3 | TAGAP | rs1738074 |  |  |  |  |  |  | 0.92 (0.88–0.96) |
| 1.16 (1.12–1.21) |
|
7p21.3 | ICA1 | rs10156091 |  |  |  |  | 1.32(1.19–1.47) |
| Â | Â | Â | Â |
7q32 | IRF5 | rs2070197 |  |  |  |  | 1.88 (1.78–1.95) |
| Â | Â | Â | Â |
8p23.1 | BLK | rs2736340 |  |  |  |  | 1.35 (1.27–1.43) |
| Â | Â | Â | Â |
8q12 | LYN | 2 SNPs |  |  |  |  | 0.77 (0.70–0.84) |
| Â | Â | Â | Â |
10p11 | NRP1 | rs2666236 |  |  |  |  |  |  | 1.21 (1.11–1.31) |
| Â | Â |
11p15.5 | KIAA1542 | rs4963128 |  |  |  |  | 0.78 (0.71–0.85) |
| Â | Â | Â | Â |
11p15.5 | INS | 187111341 |  |  |  |  |  |  | 1.25(1.15–1.35) |
| Â | Â |
12q13.2 | ERBB3 | rs2292239 |  |  |  |  |  |  | 1.28(1.21–1.35) |
| Â | Â |
12q24 | SH2B3 | rs653178 |  |  |  |  |  |  | 1.28 (1.22–1.35) |
| 1.20 (1.15–1.24) |
|
1óp11.2 | ITGAM | 3 SNPs |  |  |  |  | 1.62 (1.47–1.78) |
| Â | Â | Â | Â |
16p13.13 | CLEC16A | 3 SNPs | 0.64 (0.54–0.77) |
|  |  | 1.16 (—) |
| 0.81 (0.77–0.86) |
| 0.86 (0.82–0.91) |
|
18p11.21 | PTPN2 | 2 SNPs |  |  |  |  |  |  | 1.30 (1.22–1.40) |
| 1.17 (1.12–1.23) |
|
18q22.2 | CD226 | rs763361 |  |  |  |  |  |  | 1.16(1.10–1.22) |
| Â | Â |
22q11.21 | UBE2L3 | 2 SNPs |  |  |  |  | 1.22 (1.14–1.32) |
|  |  | 1.13(1.08–1.19) |
|
22q13.2 | SCUBEI | rs2071725 |  |  |  |  | 0.78 (0.72–0.86) |
| Â | Â | Â | Â |