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Figure 6 | Molecular Medicine

Figure 6

From: Glycine N-Methyltransferase Deficiency Affects Niemann-Pick Type C2 Protein Stability and Regulates Hepatic Cholesterol Homeostasis

Figure 6

GNMT is downregulated in fatty liver tissues. (A) IHC staining of human normal and fatty liver tissues using a monoclonal GNMT antibody. Western blot analyses of hepatic GNMT expression from WT mice fed with a high-cholesterol diet (B), high-fat diet (C) or MCD diet (D) are shown. (E) 8-wk-old ob/ob mice (n = 3–5 mice per group).

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Molecular Medicine

ISSN: 1528-3658