Table 1 Demographic/clinical data of study individuals.
From: Preserving the B-Cell Compartment Favors Operational Tolerance in Human Renal Transplantation
Study individual | OT1 | OT2 | OT3 | OT4 | OT5 | CR Group (n = 13) | Sta group (n = 19) | HI group (n = 11) |
|---|---|---|---|---|---|---|---|---|
Age (years) | 53 | 42 | 43 | 49 | 32 | 44 (27–64) | 50 (25–78) | 41 (30–57) |
Sex (F, M) | M | M | F | F | M | 4, 9 | 10, 9 | 6, 5 |
Number of grafts | 1 | 2 | 1 | 1 | 1 | 1 (n = 13) 2 (n = 1) | 1 (n = 18) | NA |
Time of transplantation (years) | 23 | 5 | 7 | 23 | 13 | 8 (4–13) | 8 (1–34) | NA |
Induction therapy | NA | Anti-CD25 | No | No | No | 5 of 13 Anti-CD25 = 4 ATG = 1 | 14 of 19 Anti-CD25 = 13 ATG + IVIG = 1 | NA |
HLA (A, B, DR) mismatches | 3 | 4 | 0 | 0 | 3 | 4.45 ± 1.75 (n = 11) NA (n = 2) | 3.83 ± 1.30 (n = 18) NA (n = 1) | NA |
Donor (living, deceased) | Living | Deceased | Living | Living | Living | 6, 7 | 16, 3 | NA |
Blood transfusion (Y, N) | NA | Y | N | Y | N | 6, 3 NA (n = 4) | 11, 3 NA (n = 5) | NA |
Acute rejection episode (Y, N) | N | Y | N | N | N | 8, 5 | 6, 13 | NA |
Viral infections (Y, N) | NA | Y | NA | N | N | 7, 5 | 4, 15 | NA |
Reason for immunosuppression interruption | Non-compliance | Non-compliance | Non-compliance | Non-compliance | Non-compliance | NA | NA | NA |
Drug-free time (years) | 6 | 1.5 | 4.1 | 8 | 4 | NA | NA | NA |