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Figure 7 | Molecular Medicine

Figure 7

From: Characterization of Bridging Integrator 1 (BIN1) as a Potential Tumor Suppressor and Prognostic Marker in Hepatocellular Carcinoma

Figure 7

Evaluation of proliferation, migration and invasion of LO2 transfected with control siRNA or BIN1-siRNA. (A) BIN1 mRNA detection in LO2 cells tranfected with control siRNA or BIN1-siRNA. All four BIN1-siRNAs silenced BIN1 expression effectively. *P < 0.05 compared with Mock-siRNA. We then randomly selected number 3 BIN1-siRNA for the subsequent experiments. (B) Proliferation detection of LO2 cells transfected with control siRNA or BIN1siRNA. LO2 cells transfected with BIN1-siRNA showed a higher growth rate than control. Experiments were performed four times (*P < 0.05 compared with Mock-siRNA). (C) Migration detection of LO2 cells transfected with control siRNA or BIN1 siRNA. LO2 cells transfected with BIN1-siRNA showed a minor difference compared with the control. (D) Invasion detection of LO2 cells transfected with control siRNA or BIN1 siRNA. LO2 cells transfected with BIN1-siRNA did not alter the invasion ability. B: ●, Mock-siRNA; ■, BIN1-siRNA.

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Molecular Medicine

ISSN: 1528-3658