Extended immunophenotype of proliferative and resting CLL fractions. Surface markers were analyzed by flow cytometry in CXCR4dimCD5bright (X) and CXCR4brightCD5dim (G) fractions. All surface molecules are depicted but CCR7 and CTLA4 were greater in CXCR4dimCD5bright fractions, in terms of percent positive cells (A) or mean fluorescence intensity (B) or both. CCR7 and CTLA4 are higher in the CXCR4brightCD5dim fraction. *P < 0.01 and §P < 0.05 (paired Student t test).