Figure 3

In vitro IL-1β-induced phosphorylation of p38 and Akt in DRG neurons of WT and GRK6^−/− mice. (A) Examplar dose-response curves for IL-1β-induced p-p38 and p-Akt. Quantification of p-p38 levels (B) and p-Akt levels (C) in DRG neurons after stimulation with increasing concentrations of IL-1β for 5 min (n = 3–7). All data are expressed as mean ± SEM. *P < 0.05; **P < 0.01.