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Figure 5 | Molecular Medicine

Figure 5

From: Effect of Nuclear Factor κB Inhibition on Serotype 9 Adeno-Associated Viral (AAV9) Minidystrophin Gene Transfer to the mdx Mouse

Figure 5

Biodistribution of minidystrophin transgene expression. Sections of muscle tissues (diaphragm, quadriceps, tibialis anterior, gastrocnemius, forelimb triceps, heart and tongue) were analyzed for human minidystrophin expression by immunohistochemistry to assess levels and distribution of transgene expression from the AAV minidystrophin vector with (AAV + NBD peptide) or without (AAV + saline) treatment with the 8K-NBD peptide. One representative mouse from each treatment group is shown. Representative images are from individual muscles of AAV + NBD peptide-treated (A–G) and AAV + saline-treated (H–N) groups. Image bar = 200 µm. L, Left; R, right.

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Molecular Medicine

ISSN: 1528-3658