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Figure 7 | Molecular Medicine

Figure 7

From: Effect of Nuclear Factor κB Inhibition on Serotype 9 Adeno-Associated Viral (AAV9) Minidystrophin Gene Transfer to the mdx Mouse

Figure 7

Muscle damage analysis. Serum from untreated C57BL/10, untreated mdx, AAV + NBD peptide-treated and AAV + saline-treated mdx mice was analyzed for the muscle protein α-sarcomeric actin, a marker of muscle degeneration. Serum levels (µg/mL) of α-sarcomeric actin were quantified using a standard curve of purified α-actin protein. (A) Representative bands from each of the treatment groups are shown. (B) Quantitative densitometry of samples from each control and treatment group is shown as mean ± SEM. *Significant difference from both untreated mdx and AAV + saline-treated mdx mice (P < 0.05); n = number of animals analyzed.

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Molecular Medicine

ISSN: 1528-3658