Figure 1From: Flexible Targeting of ErbB Dimers That Drive Tumorigenesis by Using Genetically Engineered T CellsStructure of ErbB-specific CARs. (A) Amino acid sequence of mature forms of TGF-α, EGF and the derived chimeric T1E peptide. (B) Junction of T1E peptide with the leader derived from colony-stimulating factor-1 receptor (CSF-1R). (C) Cartoon structure of T1E28z and two control CARs (EGF28z, targeted with EGF; T1NA, T1E coupled with a truncated endodomain).Back to article page