Skip to main content
Figure 3 | Molecular Medicine

Figure 3

From: Mammalian DNA Is an Endogenous Danger Signal That Stimulates Local Synthesis and Release of Complement Factor B

Figure 3

DNA stimulates factor B upregulation in vivo. (A) Factor B mRNA expression in alveolar macrophages harvested 6 h after intratracheal injection of either Lipofectamine 2000 in carrier or calf thymus DNA complexed with Lipofectamine 2000. *p < 0.005 versus control. (B) Factor B mRNA expression in peritoneal macrophages harvested at 6 h after intraperitoneal injections of either Lipofectamine 2000 in carrier, or calf thymus DNA complexed with Lipofectamine 2000. *p < 0.001 versus control; n = 6 per experimental group and experiments were repeated at least twice.

Back to article page

Molecular Medicine

ISSN: 1528-3658