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Figure 7 | Molecular Medicine

Figure 7

From: Augmenter of Liver Regeneration (ALR) Is a Novel Biomarker of Hepatocellular Stress/Inflammation: In Vitro, In Vivo and In Silico Studies

Figure 7

Time course of TNF-α- and actinomycin D-induced ALR secretion, DNA synthesis, LDH release and viability of hepatocytes. Hepatocytes were stimulated with 10 ng/mL TNF-a or actinomycin D for indicated time periods, after which the media were assessed for ALR concentration (A) and LDH release (C) and the cells for DNA synthesis (B) and viability (D). Results shown are means of triplicate determinations ± SEM from a representative of three separate experiments. *p < 0.05 versus 1 h (A, C, D) or 0 (B); **p < 0.01 versus 1 h (A, C, D) or 0 (B).

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Molecular Medicine

ISSN: 1528-3658