Figure 1

Study design. Patients enrolled in the study attended for a total of eight clinical visits. Assessments and interventions performed at each visit are detailed. Concomitant medication was continued and adverse events monitored throughout. Blinded 1:1 randomization of participants into MVC and placebo arms occurred at baseline, with drug packs lasting 24 wks. Detailed immunology and HIV clinical care was performed at screen, baseline, wks 4, 12, 16 and 24. Ab, antibody.