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Figure 6 | Molecular Medicine

Figure 6

From: Female Mice Are More Susceptible to Nonalcoholic Fatty Liver Disease: Sex-Specific Regulation of the Hepatic AMP-Activated Protein Kinase-Plasminogen Activator Inhibitor 1 Cascade, but Not the Hepatic Endotoxin Response

Figure 6

Sex differences in expression of adiponectin receptor 1 and phosphorylation status of AMPK in liver tissue in mice with steatosis induced by feeding a 30% fructose solution. (A) mRNA expression of AdipoR1 in livers of mice as well as (B) representative Western blots of hepatic phosphorylation status of AMPK in male and female mice. Expression of mRNA was determined by real time RT-PCR with Ī²-actin as a reference gene in the liver. Data are shown as means Ā± SEM (n = 6) and are specified as -fold induction. Cā€”water (control); Fā€”30% fructose solution. *p < 0.05 compared with respective water-fed control mice.

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Molecular Medicine

ISSN: 1528-3658