Table 2 Effect of chronic intake of 30% fructose solution on indices of liver steatosis in male and female mice after 16 wks.^a,b

Weight gain (g)

4.6 ± 0.3

5.7 ± 0.4

9.4 ± 0.7

14.3 ± 2.1^c

Liver weight (g)

1.1 ± 0.0

1.5 ± 0.0^d

1.6 ± 0.1

2.1 ± 0.0^d

Liver/body weight ratio (%)

5.0 ± 0.1

6.2 ± 0.1^d

5.0 ± 0.2

5.6 ± 0.2

ALT (U/L)

10.8 ± 2.8

18.0 ± 0.8

9.2 ± 1.3

9.8 ± 3.0

Neutrophils (number per field)

0.3 ± 0.1

0.7 ± 0.1^c

0.1 ± 0.1

0.4 ± 0.0

CCL2 mRNA expression (-fold induction)

2.0 ± 0.3

3.6 ± 0.6^c

1.5 ± 0.3

2.2 ± 0.4