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Figure 5 | Molecular Medicine

Figure 5

From: Glucocorticoid Receptor and Molecular Chaperones in the Pathogenesis of Adrenal Incidentalomas: Potential Role of Reduced Sensitivity to Glucocorticoids

Figure 5

Western blot analysis of the whole-cell lysate for heat shock proteins. (A) Inducible form of Hsp70 (the lower band) was expressed only in the tumor tissue (T). (B) The expression of total Hsp70 in the tumor (the sum of two protein isoforms) and adjacent normal tissue (PT) was reduced compared to the normal adrenal cortex (AC). (C) The expression of Hsp90 in control adrenal cortex, adenomatous and adjacent tissue. (D) Relative expression of Hsp90 is reduced in adrenocortical adenomas and adjacent peritumorous tissue compared to normal adrenal cortex. *p ≤ 0.01 versus control tissue.

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Molecular Medicine

ISSN: 1528-3658