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Figure 6 | Molecular Medicine

Figure 6

From: Adeno-associated Virus Serotype 8 (AAV8) Delivery of Recombinant A20 to Skeletal Muscle Reduces Pathological Activation of Nuclear Factor (NF)-κB in Muscle of mdx Mice

Figure 6

Analysis of regeneration and necrosis in quadriceps of mdx mice. (A) Muscle sections of quadriceps from mdx mice treated with AAV8-tMCK-A20 (AAV8-A20) or saline were labeled with embryonic myosin heavy chain (eMyHC) antibody (red) or IgG (green) to assess the number of regenerating fibers and necrotic fibers, respectively. Quantification of the percentage of regenerating (B) and necrotic (C) fibers is shown. n = 9 for saline-treated mdx mice; n = 12 for AAV8-tMCK-A20-treated mdx mice. Scale bar = 100 µm; *p < 0.05.

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Molecular Medicine

ISSN: 1528-3658