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Figure 5 | Molecular Medicine

Figure 5

From: Suppression of Coronary Atherosclerosis by Helix B Surface Peptide, a Nonerythropoietic, Tissue-Protective Compound Derived from Erythropoietin

Figure 5

HBSP reduces TNF-α expression in coronary atherosclerotic lesions of WHHLMI rabbits. (A) Section from control animal immunostained with negative control IgG. (B) Section from control animal immunostained with anti-TNF-α antibody. (C) Section from HBSP-treated animal immunostained with anti-TNF-α antibody. TNF-α-positive areas are visualized in brown (arrowheads). (D) Ratios of TNF-α-positive area/intimal area. Mean ± SEM; negative control IgG, n = 4; control, n = 7; HBSP, n = 8; *P < 0.01. Scale bar, 200 µm.

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Molecular Medicine

ISSN: 1528-3658