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Figure 1 | Molecular Medicine

Figure 1

From: Underexpressed CNDP2 Participates in Gastric Cancer Growth Inhibition through Activating the MAPK Signaling Pathway

Figure 1

CNDP2 expression is downregulated in human gastric cancer. (A) Immunohistochemical staining of CNDP2 in human gastric cancer and adjacent normal specimens. Negative CNDP2 staining in gastric cancer tissues (I) and positive CNDP2 staining in the matched adjacent normal tissues (II) is shown. (B, C) RT-PCR and Q-RT-PCR showed that CNDP2 expression was downregulated in gastric cancer tissues compared with the matched adjacent nontumor tissues. (D) Western blot indicated that CNDP2 expression was downregulated in paired gastric cancer tissues and nonpaired gastric cancer tissues. T, tumor tissues; N, surrounding nontumor tissues. (E) CNDP2 protein levels were analyzed in gastric adenocarcinoma tissues with different differentiation degree. (F, G) Analysis of CNDP2 expression in human gastric carcinoma cell lines. Q-RT-PCR and Western blot revealed that the expression of CNDP2 varies in gastric cancer epithelial cell lines.

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Molecular Medicine

ISSN: 1528-3658