Figure 5From: Underexpressed CNDP2 Participates in Gastric Cancer Growth Inhibition through Activating the MAPK Signaling PathwayEffects of CNDP2 on protein markers of apoptosis, the cell cycle and the MAPK pathways. (A) Protein indicators related to apoptosis (caspase 3, c-caspase 3, Bcl-2, Bax, Bad), the cell cycle (cyclin E, cyclin B1, cdc2) and the MAPK pathways (p38, p-ERK1/2, ERK1/2, p-JNK, JNK) were detected by Western blot 48 h after AGS, and SGC-7901 cells were transfected with CNDP2. GAPDH was used as the loading control. (B) The effects of CNDP2 on protein markers of MAPK pathways were assessed by Western blot in tumor xenograft tissues. *p < 0.05, **p < 0.01, from the GV142-NC or Lesh-NC group.Back to article page