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Figure 6 | Molecular Medicine

Figure 6

From: Conditional Knockout of the RNA-Binding Protein HuR in CD4+ T Cells Reveals a Gene Dosage Effect on Cytokine Production

Figure 6

BALF cellularity and serum IgE titers in HuR knockout mice with allergic airway inflammation. (A) Number of cells recovered from the BALF of immunized HuR knockout and control mice and nonimmunized mice. (B) Cellular composition represented as a percent of total cells recovered from the BALF from immunized HuR knockout mice and control mice. (C) Serum IgE levels as measured by ELISA from immunized HuR knockout or control mice and nonimmunized knockout mice. (D) BALF IL-4 and IL-13 levels were measured by using ELISA comparing immunized HuR knockout and control mice with nonimmunized knockout mice (mean ± SEM of n = 8 mice in each group; three independent experiments; *p < 0.05). N.S., not significant.

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