Figure 5
From: Decline in Serum Cholinesterase Activities Predicts 2-Year Major Adverse Cardiac Events
Measurement characteristics. Kinetic curves of thiocholine release from ATCh are shown, as measured by quantifying absorbance at 405 nm for a consecutive 1,200 s in the absence of iso-OMPA (cholinergic status) or in its presence (AChE) compared with spontaneous thiocholine release in phosphate-buffered saline (PBS) (A). Note the linearity of curves and minimal SD values. The crystallographic structures of BChE (B) and AChE (C) illustrate the general resemblance between the two enzymes. Zoom-in to the active site of BChE (D) and AChE (E); the narrower gouge in the active site of AChE can explain its capacity to hydrolyze ACh more efficiently than BChE.