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Table 2 Structural forms of HMGB1 in the blood.

From: The Expression of HMGB1 on Microparticles Released during Cell Activation and Cell Death In Vitro and In Vivo

Redox status of cysteines 23, 45 and 106 Acetylation of nuclear localization signals (NLS)

Bound to chemokines/cytokines

Bound to DNA/histones

Microparticles