Skip to main content
Figure 4 | Molecular Medicine

Figure 4

From: Decreased Langerhans Cell Responses to IL-36γ: Altered Innate Immunity in Patients with Recurrent Respiratory Papillomatosis

Figure 4

Characterization of LCs generated from peripheral blood monocytes. iLCs were generated from isolated peripheral blood monocytes by incubating blood monocytes with GMCSF, TGF-β1, and IL-4. After 6 d, they were analyzed by flow cytometry. The cells were E-cadherin+ and approximately 50% were langerin+ (A), but immature (CD83−) (B). Day 11 iLCs (C) could be induced to mature, as measured by surface expression of CD83 and HLADR, when stimulated with either IL-36γ (D) or LPS (E) for 48 h.

Back to article page

Molecular Medicine

ISSN: 1528-3658