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Figure 7 | Molecular Medicine

Figure 7

From: Decreased Langerhans Cell Responses to IL-36γ: Altered Innate Immunity in Patients with Recurrent Respiratory Papillomatosis

Figure 7

iLCs from patients are less responsive to IL-36γ. Cells from both healthy controls and RRP patients were stimulated with active IL-36γ for 4 h, and increased expression of proinflammatory cytokines and chemokines measured by q-PCR. A consistent pattern of blunted expression by the patient-derived LCs was evident, with the difference in CCL20 significant and the difference in IL-1β just missing significance. Results are the mean ± SD of at least six separate iLC cultures from controls and seven isolates from patients. *p < 0.05.

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Molecular Medicine

ISSN: 1528-3658