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Figure 8 | Molecular Medicine

Figure 8

From: Decreased Langerhans Cell Responses to IL-36γ: Altered Innate Immunity in Patients with Recurrent Respiratory Papillomatosis

Figure 8

Expression of CCL1 in iLCs correlates with severity of RRP. The level of constitutive CCL1 expression in iLCs from patients with RRP was determined by q-PCR. Expression levels in iLCs from eight controls were defined as 100%; and individual samples clustered tightly around the 100% value (not shown); there was nearly a two-log reduction in expression as severity increased in the patients, p < 0.0001. Disease severity score is a composite value of the rate of regrowth of papilloma mass divided by the time in days since the previous surgery. A score over 0.06 is classified as severe disease.

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Molecular Medicine

ISSN: 1528-3658