Figure 1

Two full thickness cutaneous wounds (4-mm diameter) were made on the back of male BALB/c mice, and wounds were evaluated by daily digital photography. Wounds were treated topically with either vehicle (hydrophilic cream, left wound) or PJ34 (100 µmol/L in hydrophilic cream; right wound) for 7 consecutive d; starting 24 h after excision. The line graph represents the mean of percent change relative to original wound size ± SEM (n = 8). *P < 0.05, **P < 0.01, ***P < 0.001: significantly different as compared between PJ34-treated (solid line) and vehicle-treated (dashed line) wounds in the same time point.