Figure 3From: Discovery of a Master Regulator of Injury and Healing: Tipping the Outcome from Damage toward RepairThe IRR mediates tissue-protective and -reparative activities via multiple intracellular pathways. Occupancy of the EPOR-β common receptor heteromer results in Janus kinase-2 phosphorylation that subsequently leads, via diverse pathways, to a decrease in injury (red outlined boxes) and to regeneration (blue outlined boxes). Image reproduced from (16).Back to article page