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Figure 2 | Molecular Medicine

Figure 2

From: Galectin-3 Ablation Enhances Liver Steatosis, but Attenuates Inflammation and IL-33-Dependent Fibrosis in Obesogenic Mouse Model of Nonalcoholic Steatohepatitis

Figure 2

Decreased number of DCs in livers of LGALS3−/− mice on HFD. Flow cytometric analysis of liver MNCs cells from WT and LGALS3−/− mice after 24 wks of HFD or standard diet. (A) CD11c+ and CD11c+F4/80− DCs with representative FACS plots and CD11c mRNA expression in liver. (B) Myeloid CD11c+DCs (CD11b+CD8a−) and lymphoid DCs (CD11b−CD8a+) with representative FACS plots. (C) Expression of MHC class II, CD80, CD86 and CCR7 on DCs. The results are shown as the means ± SEM (n = 5–6 mice/group/experiment). *P < 0.05. The results are representative of two experiments.

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Molecular Medicine

ISSN: 1528-3658