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Figure 5 | Molecular Medicine

Figure 5

From: Galectin-3 Ablation Enhances Liver Steatosis, but Attenuates Inflammation and IL-33-Dependent Fibrosis in Obesogenic Mouse Model of Nonalcoholic Steatohepatitis

Figure 5

Galectin-3 deficiency attenuates IL-33-induced liver fibrosis in mice on HFD. The effects of in vivo administered IL-33 in mice fed HFD for 12 wks. (A) H&E staining (40×). Grading of liver inflammation. (B) Picrosirius red staining (10×). Grading of liver fibrosis. (C) CD11b+ST2+ and CD11b+IL-13+ cells in liver. The results are shown as the means ± SEM (n = 5–6 mice/group/experiment). *P < 0.05, **P < 0.01.

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Molecular Medicine

ISSN: 1528-3658