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Figure 4 | Molecular Medicine

Figure 4

From: Human Parthenogenetic Embryonic Stem Cell-Derived Neural Stem Cells Express HLA-G and Show Unique Resistance to NK Cell-Mediated Killing

Figure 4

Increased apoptosis in PG NSCs after blockage of inhibitory NKL receptors. Flow cytometric analysis of activated caspase-3/7 in the target cells PG (□) or N (○) NSCs, co-cultures of effector NKL cells and target cells (E:T) at 10:1 NKL-to-target ratios, E:T in the presence of blocking ILT2 antibody (E:T anti-ILT2) or KIR2DL4 antibody (E:T anti-KIR). ***p < 0.0001, not significant (ns); n ≥ 5.

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Molecular Medicine

ISSN: 1528-3658