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Figure 5 | Molecular Medicine

Figure 5

From: H5N1 Virus Hemagglutinin Inhibition of cAMP-Dependent CFTR via TLR4-Mediated Janus Tyrosine Kinase 3 Activation Exacerbates Lung Inflammation

Figure 5

Inhibiting JAK3 results in a reduction in cytokine/chemokine hyperproduction. Cultured 16HBE cells were incubated with HA (40 µg/mL) for 12 h with or without JAK3 inhibitor VI (JAK3inh, 760 nmol/L) pretreatment, and the culture supernatants were subjected to a LiquidChip assay. *p < 0.05 versus saline control cells; #p < 0.05 versus cells incubated with HA alone.

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Molecular Medicine

ISSN: 1528-3658