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Figure 4 | Molecular Medicine

Figure 4

From: Valsartan Attenuates Atherosclerosis via Upregulating the Th2 Immune Response in Prolonged Angiotensin II-Treated ApoE−/− Mice

Figure 4

Valsartan reduces the expression of MMP-2 and MMP-9. (A) mRNA expression of MMP-2 and MMP-9 in the three groups. (B, C) Protein expression of MMP-2 and MMP-9. Treatment with Ang II induced mRNA and protein expression of MMP-2 and MMP-9, which were significantly increased compared with the control group in the aorta of the ApoE−/− mice. Group I was set as the control group (*p < 0.05 versus group II, **p < 0.01 versus group II). The values are presented as the mean ± SD; n = 4–5.

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